(1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine LORCASERIN BDBM50161646 (R)-8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine CHEMBL360328
- Smith, BM; Smith, JM; Tsai, JH; Schultz, JA; Gilson, CA; Estrada, SA; Chen, RR; Park, DM; Prieto, EB; Gallardo, CS; Sengupta, D; Dosa, PI; Covel, JA; Ren, A; Webb, RR; Beeley, NR; Martin, M; Morgan, M; Espitia, S; Saldana, HR; Bjenning, C; Whelan, KT; Grottick, AJ; Menzaghi, F; Thomsen, WJ Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity. J Med Chem 51: 305-13 (2008)